Exploring the Terpene Nerolidol:

Terpenes are the aromatic compounds found in a variety of plants, including cannabis, that contribute not only to their distinct scents and flavors but also to their potential therapeutic effects. One such terpene is nerolidol, a lesser known yet intriguing compound with a range of possible benefits. This blog post will delve into nerolidol, its presence in cannabis strains, its potential medicinal properties, and other plants that contain this versatile terpene.

What is Nerolidol?

Nerolidol, also known as peruviol or penetrol, is a naturally occurring sesquiterpene found in many plants. It emits a pleasant, woody, and slightly fruity aroma, often described as reminiscent of fresh bark and green apples. Its scent profile makes it a popular ingredient in perfumes and cosmetics.

Nerolidol in Cannabis:

In the realm of cannabis, nerolidol contributes to the complex aromatic profile of certain strains. It’s not the most common terpene in cannabis, but when present, it enhances the fragrance and may influence the overall effects of the strain. Some cannabis strains known to contain nerolidol include:

  • Jack Herer: This sativa-dominant strain is renowned for its uplifting effects and complex aroma, where nerolidol plays a subtle but significant role.
  • Skywalker OG: An indica-dominant hybrid that combines relaxing effects with a rich terpene profile, including nerolidol.
  • Sweet Skunk: Known for its pungent, sweet, and earthy aroma, this strain benefits from the presence of nerolidol.






Potential Medicinal Benefits of Nerolidol:

Research into nerolidol has uncovered several potential therapeutic properties, making it a subject of interest in the medical community. Some studies have highlighted the following benefits:

  • Antioxidant and Anti-Inflammatory: A study published in The Journal of Natural Medicines found that nerolidol exhibits significant antioxidant and anti-inflammatory activities, which may help in reducing oxidative stress and inflammation-related conditions.
  • Antimicrobial Properties: Nerolidol has demonstrated antimicrobial effects against a variety of pathogens, including bacteria and fungi. This makes it a potential candidate for use in treatments against infections and as a natural preservative in food and cosmetics.
  • Sedative Effects: Research has shown that nerolidol possesses sedative properties, which could contribute to its potential use in managing anxiety and promoting restful sleep.
  • Skin Penetration Enhancer: One study published in the European Journal of Pharmaceutics and Biopharmaceutics indicated that nerolidol might enhance the penetration of topical drugs through the skin, making it a valuable component in transdermal therapies.

Other Plants Containing Nerolidol:

Beyond cannabis, nerolidol is found in a variety of other plants and essential oils. Some notable sources include:

  • Ginger: Known for its culinary and medicinal uses, ginger contains nerolidol, contributing to its spicy and woody aroma.
  • Lavender: This widely used plant in aromatherapy and cosmetics also has nerolidol as part of its soothing fragrance.
  • Tea Tree: Tea tree oil, famous for its antimicrobial properties, includes nerolidol, enhancing its effectiveness.
  • Jasmine: Often used in perfumes, jasmine‚Äôs rich and floral scent owes part of its complexity to nerolidol.


Nerolidol is a fascinating terpene with a unique aromatic profile and a range of potential health benefits. Whether found in cannabis or other plants, its properties are being explored for various therapeutic applications. While research is ongoing, the current findings suggest promising uses for this versatile compound.


This blog post is for educational purposes only and does not constitute medical advice. Always consult with a healthcare professional before using any substances for medicinal purposes.


  • The Journal of Natural Medicines – Study on antioxidant and anti-inflammatory properties.
    • https://www.ncbi.nlm.nih.gov/pmc/?term=nerolidol+anti-inflammatory
  • Link to study on sedative effects.
    • https://www.ncbi.nlm.nih.gov/pmc/?term=nerolidol+sedative+properties


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